R spider: a network-based analysis of gene lists by combining signaling and metabolic pathways from Reactome and KEGG databases

نویسندگان

  • Alexey V. Antonov
  • Esther Schmidt
  • Sabine Dietmann
  • Maria Krestyaninova
  • Henning Hermjakob
چکیده

R spider is a web-based tool for the analysis of a gene list using the systematic knowledge of core pathways and reactions in human biology accumulated in the Reactome and KEGG databases. R spider implements a network-based statistical framework, which provides a global understanding of gene relations in the supplied gene list, and fully exploits the Reactome and KEGG knowledge bases. R spider provides a user-friendly dialog-driven web interface for several model organisms and supports most available gene identifiers. R spider is freely available at http://mips.helmholtz-muenchen.de/proj/rspider.

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عنوان ژورنال:

دوره 38  شماره 

صفحات  -

تاریخ انتشار 2010